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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
12.42
Human Site:
T332
Identified Species:
18.22
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
T332
L
A
I
K
R
K
R
T
E
A
L
E
Q
G
G
Chimpanzee
Pan troglodytes
XP_518193
305
34323
Q296
K
R
T
E
A
L
E
Q
G
G
L
P
K
K
L
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
T332
L
A
T
K
R
K
R
T
E
A
L
E
Q
G
G
Dog
Lupus familis
XP_850424
354
39795
T340
V
A
T
K
R
K
R
T
Q
A
L
E
Q
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
A332
V
A
T
K
R
K
R
A
E
A
L
E
Q
G
I
Rat
Rattus norvegicus
P51952
329
37122
K322
P
A
M
A
T
K
R
K
R
A
E
A
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
A310
A
V
A
K
R
K
R
A
E
A
M
E
Q
G
G
Chicken
Gallus gallus
P13863
303
34670
T294
F
D
D
L
D
K
S
T
L
P
A
N
L
I
K
Frog
Xenopus laevis
P20911
352
39672
T338
L
G
I
K
R
K
R
T
E
G
M
D
Q
K
D
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
P325
H
E
F
T
V
D
R
P
L
H
E
S
V
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
K332
G
D
T
K
P
A
L
K
R
K
L
V
E
T
T
Honey Bee
Apis mellifera
XP_395800
321
36188
D311
R
K
L
L
E
S
M
D
G
A
S
L
A
K
R
Nematode Worm
Caenorhab. elegans
P34556
332
38277
G323
D
T
S
K
L
P
A
G
N
Y
R
G
E
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
F287
Q
A
L
E
H
E
Y
F
K
D
L
E
V
V
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
P329
A
I
T
V
Q
S
P
P
R
K
L
R
R
V
M
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
D298
K
E
L
P
P
P
S
D
P
S
S
I
K
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
6.6
93.3
80
N.A.
73.3
26.6
N.A.
66.6
13.3
60
6.6
N.A.
13.3
6.6
6.6
N.A.
P-Site Similarity:
100
20
93.3
93.3
N.A.
80
33.3
N.A.
73.3
13.3
73.3
6.6
N.A.
20
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
38
7
7
7
7
7
13
0
44
7
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
13
7
0
7
7
0
13
0
7
0
7
0
0
13
% D
% Glu:
0
13
0
13
7
7
7
0
32
0
13
38
13
7
7
% E
% Phe:
7
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
0
0
0
0
7
13
13
0
7
0
32
25
% G
% His:
7
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
13
0
0
0
0
0
0
0
0
7
0
13
7
% I
% Lys:
13
7
0
50
0
50
0
13
7
13
0
0
13
19
7
% K
% Leu:
19
0
19
13
7
7
7
0
13
0
50
7
13
7
7
% L
% Met:
0
0
7
0
0
0
7
0
0
0
13
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% N
% Pro:
7
0
0
7
13
13
7
13
7
7
0
7
0
0
0
% P
% Gln:
7
0
0
0
7
0
0
7
7
0
0
0
38
0
13
% Q
% Arg:
7
7
0
0
38
0
50
0
19
0
7
7
7
0
13
% R
% Ser:
0
0
7
0
0
13
13
0
0
7
13
7
0
0
0
% S
% Thr:
0
7
38
7
7
0
0
32
0
0
0
0
0
7
7
% T
% Val:
13
7
0
7
7
0
0
0
0
0
0
7
13
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _